Dr. Jonathan D'Cunha

Dr. Jonathan D'CunhaDr. Jonathan D'CunhaDr. Jonathan D'Cunha
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Dr. Jonathan D'Cunha

Dr. Jonathan D'CunhaDr. Jonathan D'CunhaDr. Jonathan D'Cunha
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A Visionary in Cardiothoracic Surgery

Dr. Jonathan D'Cunha is a renowned surgeon-scientist who has dedicated his career to advancing the field of cardiothoracic surgery through innovative research, surgical expertise, and medical education. Dr. D'Cunha continues to push the boundaries of patient care and surgical techniques.

Educational Background and Early Career

  • MD/PhD from Medical College of Wisconsin
  • PhD in Microbiology/Immunology
  • Postdoctoral Fellowship at the University of Maryland/National Institutes of Health 
  • General Surgery training and Cardiothoracic Surgical Fellowship at the University of Minnesota

Research and Innovation

Dr. D'Cunha's research journey began with the discovery of ISG15, a novel interferon-induced immunomodulatory cytokine. His work established ISG15 as a potential tool in fighting viral infections and treating malignancies by enhancing the immune system. This groundbreaking research set the foundation for his future contributions to the field. 

Surgical Expertise

Specializing in minimally invasive and robotic thoracic surgery, Dr. D'Cunha is an expert in treating lung, mediastinal, and esophageal cancers. His clinical focus extends to complex lung failure cases, including:


  • Lung transplantation
  • Extracorporeal Membrane Oxygenation (ECMO)
  • Ex Vivo Lung Perfusion (EVLP)


As one of the first surgeons to use EVLP in clinical practice in the United States, Dr. D'Cunha has been instrumental in advancing this life-saving technology.

Leadership and Accomplishments

Throughout his illustrious career, Dr. D'Cunha has held several prestigious positions:


  • Surgical Director of Lung Transplantation at the University of Pittsburgh
  • Chief of the Division of Lung Transplantation/Lung Failure at the University of Pittsburgh 
  • Surgical Director of ECMO at the University of Pittsburgh 
  • Vice Chair of Research for the Department of Cardiothoracic Surgery at the University of Pittsburgh 


Commitment to Education

Dr. D'Cunha's passion for medical education has been a constant throughout his career. His achievements in this area include:


  • Developing a novel course for medical students transitioning to residency, later adopted by the American College of Surgeons
  • Receiving the University of Minnesota Outstanding Medical School Educator award
  • Being named the Association for Surgical Education Surgical Educator of the Year in 2011


He has mentored hundreds of students, residents, fellows, and faculty, shaping the next generation of medical professionals.

Research and Publications

As an internationally recognized expert, Dr. D'Cunha has authored hundreds of manuscripts, abstracts, and book chapters. His research interests span all aspects of thoracic oncology and lung transplantation, contributing significantly to the body of knowledge in these fields.

Dr. Jonathan D'Cunha continues to lead by example, combining surgical excellence, innovative research, and dedicated mentorship to advance the field of cardiothoracic surgery and improve patient outcomes.


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